产品货号:
Z15404
中文名称:
DR5/TNFRSF10B抗体
英文名称:
Anti-DR5/TNFRSF10B Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DR5/TNFRSF10B Antibody |
指标别名 | CD262;Death receptor 5;DR5;KILLER;KILLER/DR5;TNFRSF10B;TRAIL R2;TRAIL receptor 2;TRAILR2;TRICK2;TRICK2A;TRICK2B;TRICKB;ZTNFR9 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | TNFRSF10B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human DR5/TNFRSF10B recombinant protein (Position:Q70-K427). |
实际分子量 | 48KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | TNFRSF10B(Tumor necrosis factor receptor superfamily,member 10b) is a human gene.It is also known as DR5,CD262,KILLER,TRICK2,TRICKB,ZTNFR9,TRAILR2,TRICK2A,TRICK2B,TRAIL-R2,KILLER/DR5.The protein encoded by this gene is a member of the TNF-receptor superfamily,and contains an intracellular death domain.This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L),and transduces apoptosis signal.Mice have a homologous gene,tnfrsf10b that has been essential in the elucidation of the function of this gene in humans.Studies with FADD-deficient mice suggested that FADD,a death domain containing adaptor protein,is required for the apoptosis mediated by this protein.By analysis of radiation hybrid panels,this gene is mapped to chromosome 8p22-p21.Northern blot analysis indicated that TRAILR2 was expressed as a 4.4-kb mRNA in all tissues tested,with the highest levels of expression in peripheral blood lymphocytes,spleen,and ovary. |
Uniprot ID | O14763 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | TNFRSF10B TNF receptor superfamily member 10b |
蛋白名全称 | Tumor necrosis factor receptor superfamily member 10B |
推荐稀释比 | Western blot(WB) 1:500~2000 ELISA 1:100~1000 |
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